The higher seeded team reaching the World Series will have last at-bats in Games 1 and 2 and, if needed, Games 6 and 7, not necessarily the team with the best record.
The specification was contained in the July 23 agreement between Major League Baseball and the players' association to expand the playoffs following a regular season shortened by the coronavirus.
The change means a No. 1 seed from one league with fewer regular-season wins than a lower seed from the other league would have the "home-field advantage" for the World Series should they both win pennants.
In the event both pennant winners have the same seed, regular-season winning percentage would decide which team is "home" for the first two games.