Four minor league pitchers were suspended 50 games each by the commissioner's office Tuesday for violating baseball's minor league drug program, the first penalties since the sport toughened its rules during the offseason. Two of the pitchers were in the Cincinnati Reds' organization: Ramon Ramirez and Justin Mallet. Also suspended were Waner Mateo of the New York Mets and Ryan Rafferty of the Kansas City Royals.