Apr 30, 2022

• The San Francisco Giants acquired INF Mike Ford from Seattle in exchange for cash considerations.
• The Oakland Athletics claimed RHP Domingo Tapia off waivers from the Kansas City and optioned him to Las Vegas (PCL).
• The Los Angeles Angels signed INF Christian Sepulveda to a rookie-level contract.

Apr 29, 2022

• The San Francisco Giants released LHP Darien Nunez.

Apr 28, 2022

• The Boston Red Sox claimed OF Jaylin Davis off waivers from San Francisco and optioned him to Worcester (IL).

Apr 26, 2022

• The Seattle Mariners traded INF Kevin Padio to San Francisco in exchange for cash considerations.

Apr 24, 2022

• The Arizona Diamondbacks traded RHP Matt Peacock to Kansas City for cash considerations.

Apr 23, 2022

• The Arizona Diamondbacks traded OF Stuart Fairchild to Seattle for cash considerations.

Apr 22, 2022

• The Miami Marlins agreed to terms with INF Joey Wendle on a one-year contract.

Apr 21, 2022

• The San Francisco Giants acquired RHP Cory Abbott in trade with Chicago Cubs in exchange for cash considerations and Optioned him to Sacramento (PCL).

Apr 20, 2022

• The Atlanta Braves acquired RHP Jesse Chavez and cash from Chicago Cubs for LHP Sean Newcomb.
• The Chicago Cubs acquired LHP Sean Newcomb from Atlanta for RHP Jesse Chavez and cash.

Apr 19, 2022

• The Colorado Rockies agreed to terms with LHP Kyle Freeland on a five-year contract.
• The Arizona Diamondbacks claimed RHP Jacob Webb off waivers from Atlanta and optioned to Reno (PCL).

Apr 18, 2022

• The Seattle Mariners announced the retirement of Rebecca Hale, senior director of public information.

Apr 17, 2022

• The Seattle Mariners acquired RHP Riley O'Brien from Cincinnati in exchange for a player to be named later or cash considerations.

Apr 14, 2022

• The Pittsburgh Pirates agreed to terms with OF Bryan Reynolds on a two-year contract.

Apr 13, 2022

• The Kansas City Royals placed LHP Daniel Tillo on waivers.