Aaron Judge might be headed back to the injured list just a few days after the New York Yankees activated him.

Judge appeared to re-injure his right leg running to second base on Wednesday night. Two innings after that, Judge was lifted for a defensive replacement. The Yankees had just removed Judge from the IL on Tuesday.

"He tightened up again in that calf area running to second base, so we'll see where he's at," Aaron Boone said. "Doesn't seem to be overly serious but enough that we needed to get him out of there. [It's] frustrating, no question. Obviously, he's very frustrated, but we'll see where we're at as we get through it tonight and where he's at feeling tomorrow."

Boone said that it's "possible" Judge could be headed for another IL stint, but added, "I think we'll have a better feel later tonight and into tomorrow exactly where he's at."

The Washington Nationals will be without Stephen Strasburg for the remainder of the season.

Strasburg has been diagnosed with carpal tunnel neuritis and will undergo season-ending surgery.

The right-hander has been limited to two starts because of the nerve issue. He has a 10.80 ERA in just five innings pitched.

Yordan Alvarez has played just two games this season and won't take the field for the Houston Astros again in 2020.

Alvarez suffered a partial tear of the patella tendon in his right knee and will undergo surgery next week.

"I asked [Alvarez] when did he start having these problems, and he said back in Double-A," Dusty Baker said. "Most of the time when you have knee problems, they don't subside very quickly. And when they do, they have a history of coming back."

Alvarez, 23, opened the 2020 season on the injured list because of COVID-19. He played his first game of the 2020 season on Friday, and in two games and nine plate appearances, he put up a slash line of .250/.333/.625 with one home run.

The New York Yankees have three of their best hitters on the injured list, but it appears as though Aaron Judge will be back soon.

In addition to Judge, Giancarlo Stanton (hamstring) and DJ LeMahieu (left thumb) are both sidelined.

On Sunday, Judge said his strained calf feels back to 100 percent and it looks like he'll only need the minimum 10 days on the IL. He can be reactivated on August 22.

Judge is hitting .290/.343/.758 with nine home runs and 20 RBI in 17 games.

Giancarlo Stanton could miss up to a month with a Grade 1 hamstring strain, according to the New York Yankees.

Aaron Boone said a "reasonable" recovery timeline would be three to four weeks.

Stanton was placed on the injured list on Sunday. He was hitting .293/.453/.585 with three home runs and seven RBI.

The New York Yankees have placed Giancarlo Stanton on the injured list with a strained left hamstring.

Stanton suffered the injury while running the bases during the second game of Saturday's doubleheader against the Tampa Bay Rays.

The 30-year-old was hitting .293/.453/.585 with three home runs and three doubles through 14 games.

Stanton played just 18 games last season because of a biceps strain followed by a knee injury.

Shohei Ohtani has been essentially ruled out for the remainder of the season as a pitcher, but he still wants to be a two-way player in hte future. 

"If it comes down to them telling me to just focus on hitting or focus on pitching, I will listen," Ohtani said through an interpreter on Wednesday, two days after being diagnosed with a Grade 1-2 strain of the flexor pronator mass in his pitching arm. "But ideally, I would like to leave the window open for me to do both."

Ohtani has contributed only 53⅓ innings as a pitcher in his MLB career.

Ohtani suffered a Grade 2 sprain of his ulnar collateral ligament in June 2018, then underwent Tommy John surgery four months later.

Max Scherzer left his tart on Wednesday after one inning due to a tweaked right hamstring.

"The best decision was just to get out of the game," said Scherzer.

Scherzer revealed afterward that he felt something wrong with the hamstring before his previous start six days earlier against Toronto.

Mike Soroka will miss the rest of the 2020 season with a torn right Achilles tendon.

After completing his follow-through, Soroka broke toward first to cover the bag -- only to go down on his first step off the mound. Soroka let out a scream as it happened.

"I heard him yell," Freddie Freeman said. "There's no sugarcoating it. It's just a terrible injury for somebody so young, so bright, so determined to be great at this game."

A native of Canada, Soroka went 13-4 with a dazzling 2.68 ERA in 2019, earning a spot in the All-Star Game.

Shohei Ohtani has a Grade 1-2 strain of the flexor pronator mass near his surgically repaired right elbow and will cease pitching for the foreseeable future.

The Angels said Ohtani is traveling with the team to Seattle and that his status as a designated hitter is "day to day."

Ohtani, who underwent Tommy John surgery in October 2018, has recorded only five outs in his first two starts of the season.