The Twins have opened trade discussions for Johan Santana by asking the Yankees for a package of at least three young players that would include one of their three top starters -- Joba Chamberlain, Phil Hughes or Ian Kennedy -- plus center fielder Melky Cabrera. The Twins are talking with several teams and are asking for a large return for their two-time Cy Young winner. From Boston, they asked about one of two top young pitchers -- Clay Buchholz or Jon Lester -- plus center field prodigy Jacoby Ellsbury, league sources told SI.com. The Mets, Dodgers, Angels and Mariners are seen as other potential big players for Santana, who went 15-13 this season with a 3.33 ERA. The Twins began canvassing prospective suitors after their extension offer of $80 million over four years fell well short of Santana's expectations. The 28-year-old ace with the 93-44 career record is slated to make $13.25 million in 2008 and is eligible for free agency after the season.