Johan Santana finally lost at the Metrodome, an amazing streak nearly two years old that ultimately ended against Tampa Bay. Carl Crawford's inside-the-park home run and Scott Kazmir's eight sharp innings helped Tampa Bay beat Santana and the Twins 4-2 on Friday night. Despite striking out 10 in seven innings, including five of the last six batters he faced, Santana lost at home for the first time since Aug. 1, 2005.