Carlos Lee became the 16th active player with 2,000 hits on Saturday when he singled off Mets starter R.A. Dickey.
Lee received a standing ovation from the crowd at Minute Maid Park when the achievement was acknowledged.
He is hitting .243/.278/.375 this season.
Lee's first hit came on May 7, 1999, a home run in his first major league at-bat.
Carlos Lee Notches 2,000th Hit