Astros vs. Guardians: Odds, spread, over/under - May 1

The Houston Astros (10-19) and the Cleveland Guardians (19-10) will square off on Wednesday, May 1 at Minute Maid Park, with Justin Verlander getting the nod for the Astros and Triston McKenzie toeing the rubber for the Guardians. The first pitch will be thrown at 8:10 PM ET.

Bookmakers list the Astros as -175 moneyline favorites, while giving the underdog Guardians +145 moneyline odds. The over/under for the contest has been set at 8.5 runs.

Astros vs. Guardians Time and TV Channel

• Date: Wednesday, May 1, 2024
• Time: 8:10 PM ET
• TV: SCHN
• Location: Houston, Texas
• Venue: Minute Maid Park
• Probable Pitchers: Verlander - HOU (1-0, 1.74 ERA) vs McKenzie - CLE (2-2, 4.91 ERA)

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Astros vs. Guardians Betting Odds, Run Line and Total

Take a look at the odds, run line and over/under for this matchup available at individual sportsbooks.

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Read More About This Game

• How to Watch Astros vs. Guardians
• Astros vs. Guardians Predictions

Astros vs. Guardians Betting Trends and Insights

• The Astros have been favorites in 23 games this season and won eight (34.8%) of those contests.
• The Astros have a 3-2 record (winning 60% of their games) when they have played as moneyline favorites of -175 or shorter.
• The moneyline for this contest implies a 63.6% chance of a victory for Houston.
• The Astros were favored on the moneyline for nine of their last 10 games, and they finished 4-5 in those matchups.
• Over its last 10 matchups, Houston and its opponents combined to hit the over one time (all 10 of the games had set totals).
• The Guardians have been underdogs in 13 games this season and have come away with the win eight times (61.5%) in those contests.
• The Guardians have played as an underdog of +145 or more just one time this year and came away with a loss in that game.
• In four games as underdogs over the last 10 matchups, the Guardians have a record of 1-3.
• In the last 10 games with a total, Cleveland and its opponents have combined to hit the over six times.

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Futures Odds

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