Astros vs. Cubs: Odds, spread, over/under - April 25

As they try to secure the series sweep on Thursday, April 25, Javier Assad will take the hill for the Chicago Cubs (15-9) as they match up against the Houston Astros (7-18), who will answer with Justin Verlander. The first pitch will be thrown at 2:20 PM ET at Wrigley Field.

The favored Astros have -125 moneyline odds against the underdog Cubs, who are listed at +105. The matchup's over/under is set at 7.5 runs.

Astros vs. Cubs Time and TV Channel

• Date: Thursday, April 25, 2024
• Time: 2:20 PM ET
• TV: SCHN
• Location: Chicago, Illinois
• Venue: Wrigley Field
• Probable Pitchers: Verlander - HOU (1-0, 3.00 ERA) vs Assad - CHC (2-0, 2.11 ERA)

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Astros vs. Cubs Betting Odds, Run Line and Total

Check out the odds, run line and over/under for this matchup at multiple sportsbooks.

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Read More About This Game

• Astros vs. Cubs Predictions
• How to Watch Astros vs. Cubs

Astros vs. Cubs Betting Trends and Insights

• The Astros have won five, or 26.3%, of the 19 games they've played as favorites this season.
• In games they have played as moneyline favorites with odds of -125 or shorter, the Astros have a record of 4-8 (33.3%).
• Sportsbooks have implied with the moneyline set for this matchup that Houston has a 55.6% chance to win.
• The Astros went 3-4 over the seven games they were moneyline favorites in their last 10 matchups.
• In its last 10 outings, Houston and its opponents combined to hit the over two times (all 10 of the games had set totals).
• The Cubs have won in nine, or 56.2%, of the 16 contests they have been named as odds-on underdogs this year.
• This season, the Cubs have come away with a win six times in nine chances when named as an underdog of at least +105 or worse on the moneyline.
• The Cubs have played as underdogs in six of their past 10 games and won five of those contests.
• In the last 10 games with a total, Chicago and its opponents have failed to hit the over seven times.

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