Major league players and owners agreed to toughen penalties for steroid use to a 50-game suspension for a first failed test, 100 games for a second and a lifetime ban for a third. Baseball also will test for amphetamines for the first time starting next year under the deal, which must be ratified by both sides. Baseball's current steroid penalties are a 10-day suspension for a first offense, 30 days for a second offense and 60 days for a third. The earliest a player could be banned for life is a fifth offense. "This is an important step to reaching our goal of ridding our sport of performance-enhancing substances and should restore the integrity of and public confidence in our great game," commissioner Bud Selig said in a statement. "I appreciate the effort put forward by the players' association and our players in reaching this new agreement."