Carlos Ruiz has been suspended for the first 25 games of the 2013 season following a positive test for an amphetamine.

He had a career year in 2012, hitting .325 with 16 homers and 68 RBIs in 114 games.

"I am sincerely regretful for my mistake in taking a prohibited stimulant," Ruiz said in a statement.

"I apologize to my teammates, the Phillies organization and the Philadelphia fans. I will serve the imposed 25-game suspension to begin the season and I look forward to returning to the field and working toward bringing a championship back to Philadelphia in 2013."

This had to be Ruiz's second positive test for a stimulant. An initial positive for a stimulant does not trigger a suspension, only that the player must undergo follow-up testing.

Yasmani Grandal has been suspended 50 games without pay after testing positive for use of a banned substance.

The substance was testosterone.

The rookie batted .297/.394/.469 with eight home runs in 60 games for the Padres.

"We were disappointed to learn of the suspension of Yasmani Grandal for violating Major League Baseball's Joint Drug Prevention & Treatment Program," the Padres said in a statement. "We fully support Major League Baseball's policy and its efforts to eliminate performance enhancing drugs from our game. Per the protocol outlined by Major League Baseball's collective bargaining agreement, we will not comment further on this matter."