As arguably the two best right-handed pitchers of their generation, the relationship between the Rangers' Max Scherzer and the Astros' Justin Verlander has taken many forms.

It also has evolved from some early career friction as young teammates with the Tigers, mostly thanks to their brief time as teammates with the Mets.

In Detroit, the two future Hall of Famers were in competition with each other as well as opponents. They've also been on teams that competed against each other for playoff spots and championships. In New York, they were teammates again, but older and wiser.

On Wednesday, the relationship will take a form it never has before: opposing pitchers on the mound.