The Tigers may not have a healthy Carlos Guillen in the lineup on Opening Day. Guillen received treatment on his surgically repaired left knee on Monday while his teammates were on the field. His knee has been sore for the past few days, manager Jim Leyland said, and it put his rehab process on hold. If he can't play, Scott Sizemore, Will Rhymes and Danny Worth would compete for Detroit's starting role at second base.